Jubayer Hossain - Multiomics and Machine Learning

Multiomics · Cancer Genomics · Machine Learning

Jubayer Hossain

Multiomics scientist decoding cancer biology from public transcriptomic data.

I build reproducible computational workflows on public omics data — meta-analysing bulk RNA-Seq cohorts, constructing harmonised single-cell atlases, and applying machine learning to high-dimensional data for biomarker discovery.

I founded DeepBio Limited, a Dhaka-based AI and bioinformatics company, and CHIRAL Bangladesh, a non-profit research institute that has trained 3,000+ early-career researchers. I teach through DeepBio Academy and mentor students from raw sequencing data to published analysis.

Bulk RNA-Seq Single-Cell Spatial Transcriptomics Graph Neural Networks Cancer Genomics
16 Publications 19 Talks 3,000+ Researchers trained
Publications Talks Projects CV

Research focus

Applied Computational Biology

Bulk RNA-Seq Analysis Differential expression, pathway & signature analysis across cancer cohorts. Single-Cell Analysis Cell-state atlases, tumor heterogeneity & cell–cell communication from scRNA-seq. Spatial Transcriptomics Tissue architecture, niche deconvolution & spatially resolved gene programmes. Graph Neural Networks Modeling gene regulatory networks & spatial cell-graphs in cancer biology.

Speaking

Talks & Presentations

2026

Single-Cell Transcriptomic and Network Pharmacology Insights into the Therapeutic Potential of Withania somnifera-Derived Phytochemicals Against Cisplatin-Resistant Ovarian Cancer

IEEE BECITHCON 2026

2026

Fezf2-Mediated Cortical Development: Multi-Omics Single-Cell Analysis

Network of Young Biotechnologists Bangladesh · Dhaka, Bangladesh

2025

Identification of Subtype-Specific Prognostic Biomarkers in Esophageal Carcinoma through Integrated Bioinformatics Analysis

9th BSM Annual Conference · University of Dhaka, Bangladesh

2025

Network-Driven Bioinformatics Approach Uncovers Prognostic Signatures and Therapeutic Targets in Pancreatic Ductal Adenocarcinoma

9th BSM Annual Conference · University of Dhaka, Bangladesh

2025

Bioinformatic Analysis of Transcriptomic Data Reveals Molecular Signatures Driving Colorectal Cancer

9th BSM Annual Conference · University of Dhaka, Bangladesh

2025

Comparative Transcriptomic Meta-Analysis Reveals Shared and Distinct Transcriptional Networks and Pathway Crosstalk in Hepatocellular Carcinoma for Biomarker and Therapeutic Target Identification

9th BSM Annual Conference · University of Dhaka, Bangladesh

2018

State the Art of Microbial Genome Analysis

Jagannath University · Dhaka, Bangladesh

2015

Computational Biology and Bioinformatics Research in Resource-Limited Settings: Strategies, Tools and Opportunities

Jagannath University Higher Study and Research Society · Dhaka, Bangladesh

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Tools & Tutorials

Featured Tools & Tutorials

Video playlist

R for Research

Video lectures covering R programming fundamentals, data manipulation, statistical testing, and visualization for researchers.

Watch playlist →
Video playlist

Cancer Bioinformatics

Video tutorials on cancer genomics analysis, covering TCGA data access, mutation analysis, survival modeling, and multi-omics integration.

Watch playlist →
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Publications

Preprints

Dosage-dependent disruption of corticofugal neuron development by Fezf2 loss

Hossain, M. J., Abhi, N. I., Islam, M. M., Das, S., Tasneem, E., & Tasnim, M.
bioRxiv, 2026Preprint

Evaluating the false-positive rate of single-cell copy-number and malignant-cell classifiers

Hossain, M. J., & Dev, P. C.
bioRxiv, 2026Preprint

A donor-level map of immune sex differences

Hossain, M. J., Dev, P. C., Nawar, T., Arony, T. A., Hoque, M., Chowdhury, D., & Rahma, M. A.
bioRxiv, 2026Preprint

Multi-cohort transcriptomic analysis reveals a convergent immune-myeloid hub associated with poor prognosis in glioblastoma

Hossain, M. J., Ahmed, E., Shafin, R. H., Islam, J., Chowdhury, M. H., Ali, M. L., Dewanjee, S., & Hosain, M. M.
bioRxiv, 2026Preprint

External validation of a single-cell multi-omics target prioritization pipeline in breast cancer

Hossain, M. J., & Abhi, N. I.
bioRxiv, 2026Preprint

Graph Neural Network for predicting immunosuppressive spatial niches in glioblastoma from 10x Visium spatial transcriptomics

Hossain, M. J., & Dev, P. C.
bioRxiv, 2026Preprint
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Peer-Reviewed

Recent Publications

Earlier Publications (10 more)
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Founded & led

Initiatives

Non-profitJune 2020 – Present

CHIRAL Bangladesh

Founder & Capacity Building Director

Non-profit research institute building computational research capacity across Bangladesh and South Asia.

3,000+Researchers Trained
20+Publications
40+Conference Papers
chiralbd.github.io →
EdTech Platform2025 – Present

DeepBio Academy

Founder & Lead Instructor

Online academy teaching bioinformatics and computational biology through expert-led, project-based courses.

500+Students
6+Courses
4.9/5Rating
deepbioacademy.com →
Research StartupJan 2025 – Present

DeepBio Limited

Founder, CEO & Bioinformatics Scientist

AI and bioinformatics company turning multi-omics data into biomarker discovery and diagnostics for global health.

13+Team
250+Genomes
12+Services
deepbioltd.com →
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Updates

News

COL13A1 and COL23A1 identified as thyroid cancer biomarkers — Published in Health Science Reports. Read →

Rainbow trout RNA-Seq meta-analysis out in BMC Genomics — Conserved stress responses across four public datasets. Read →

WNT gene family in breast cancer published in Scientific Reports — Prognostic significance and immunological roles. Read →

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Training & mentorship

Open Programmes

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